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OmniLyse® Inside Kits

For Hard-To-Lyse Sample Prep in Minutes

Rapid Lysis

Tissue Homogenization

Bacterial gDNA Extraction

 

OmniLyse® Cell Lysis Kit

OmniLyse® High Load Lysis Kit

for high concentration

OmniLyse® X Cell & Tissue Lysis Kit 2.0mL

OmniLyse® X Cell & Tissue Lysis Kit 0.5mL

for viscous liquids, tissues, biofilms, and other hard-to-lyse sample types

 

microHomogenizer 2.0mL*

microHomogenizer 1.5mL*

*Available with or without grinding media

PureLyse® Bacterial gDNA Extraction Kit

for Gram-Positive or Gram-Negative Bacterial gDNA Extraction

  • Miniaturized mechanical lysis

  • Proven for hard-to-lyse microbes

  • Rapid & highly efficient

  • Easy-to-use & portable

  • Low-power, -heat, -noise, -volume

  • Unique flow-through format

  • Disposable (RoHS Compliant)

  • Multiple US & Intl. patents

  • Quick and convenient sample preparation in minutes

  • No need for lengthy overnight tissue digestion

  • Effective homogenization for various tissue types, including mouse heart, tail, liver, and brain, as well as plant tissues

  • Utilizes microfuge tubes provided by ClaremontBio

  • Versatile for use with a wide range of downstream applications

  • Suitable for DNA extraction, RNA extraction, and protein purification

  • Rapidly extracts gDNA from bacterial samples in minutes

  • Works with gram-positive & gram-negative cells, yeast, mammalian cells, spores, and many more

  • Disposability and portability allow PureLyse® Kits to be stored under normal laboratory condition

  • No centrifugation steps

  • Kits can be simply thrown away without any harm to the environment


OmniLyse X 2mL Cell & Tissue Lysis Device Item# 01.522.48 OmniLyse® X 2mL Cell & Tissue Lysis Device - 48 Preps

The OmniLyse® X 2mL features an open top that allows for lysing of viscous liquids, tissues, biofilms, and various other hard-to-lyse sample types up to 1mL.

Price :$540.00
PURELYSE® BACTERIAL GDNA EXTRACTION KIT Item# 01.350.48 PureLyse® Bacterial gDNA Extraction Kit - 48 Preps

The PureLyse® system is an innovative, compact, and disposable kit that enables ultra-rapid lysis and DNA extraction for various laboratory applications.

Price :$630.00
OmniLyse - 48 Preps Item# 01.340.48 OmniLyse® Cell Lysis Kit - 48 Preps

The OmniLyse® Cell Lysis Device for rapid cell lysis in the field or at the lab bench.

Price :$540.00
High Load Cell Lysis Kit Item# 01.335.48 OmniLyse® HL Kit - 48 Preps

The OmniLyse® HL features a larger inlet and outlet for easy handling of samples in bigger quantities than the standard OmniLyse®.

Price :$540.00
OmniLyse® Family Assortment Pack Item# 01.500.24 OmniLyse® Family Assortment Pack - 24 Preps

Discover the perfect lysis method for your application with our convenient assortment pack.
Your all-in-one solution for cell and tissue lysis.

Price :$360.00
OmniLyse X 0.5mL Cell Lysis Kits 48 Preps Item# 01.532.48 OmniLyse® X 0.5mL Cell & Tissue Lysis Device - 48 Preps

The OmniLyse® X 0.5 mL features an open top that allows for lysing of viscous liquids, tissues, biofilms, and various other hard-to-lyse sample types up from 200-500 µL.

Price :$540.00
microHomogenizerâ„¢ Tissue Homogenizer Item# 04.280.48 microHomogenizer - with 1.5mL Tubes - 48 Pack

microHomogenizer kits for tissue homogenization in a microfuge tube. Beads not included.

Price :$500.00
microHomogenizer Tissue Homogenizer Item# 04.282.48 microHomogenizer - with 2.0mL Tubes - 48 Pack

microHomogenizer kits for tissue homogenization in a microfuge tube. Beads not included.

Price :$500.00

"OmniLyse methods provided the greatest consistent yield of genomic DNA."- Irwin et al. BMC Microbiology (2014) 14:326 - USDA publication - Near-Quantitative Sampling of Genomic DNA from Various Food-Borne Eubacteria


CBIO devices can be used in-line with many nucleic acid extraction kits, to improve extraction of DNA and RNA. Note: CBIO devices are not compatible with buffers that include phenol, chloroform or TRIzol. Please contact CBIO with any questions about specific applications. Using any of the OmniLyse® family of devices, it is fast and straightforward to mechanically lyse challenging gram-positive bacteria and other tough-walled organisms, including yeast and protozoan parasites, without time-consuming and less effective digestion or chemical lysis steps. Typically, unbiased lysis yields of approximately 90% can be achieved in less than one minute or approximately 99% in three minutes (up to 5 minutes for oocysts) — ideal for downstream genomic and proteomic analyses. Our patented micro-motor driven, bead-based design generates high shear force to quickly and economically disrupt hard-to-lyse organisms, including Staphylococcus, Bacillus spores, Clostridium, Mycobacteria, Candida, or Giardia/Cryptosporidium/Cyclospora oocysts, within difficult sample matrices, such as stool, soil, blood, or sputum.

OmniLyse® -inside technologies and related extraction methods are covered under one or more ot the following patents owned by Claremont BioSolutions LLC:

US 8,663,974 (issued Mar 4, 2014)

JP 5663311 (issued Dec 12, 2014)

JP 5711227 (issued Mar 13, 2015)

US 9,260,475 (issued Feb 16, 2016)

US 9,428,725 (issued Aug 30, 2016)

EP 2232259 (issued Oct 12, 2016)

JP 6040268 (issued Nov 11, 2016)

AU 2010266034 (issued Mar 30, 2017)

EP 2446047 (issued Oct 18, 2017)

US 9,873,860 (issued Jan 23, 2018)

HK 1171052 (issued Aug 3, 2018)

US D829,339 (issued on Sep 25, 2018)

US 10,428,301 (issued on Oct 1, 2019)

US 10,801,001 (issued on Oct 13, 2020)

US 11,286,447 (issued on Mar 29, 2022)

US 11,286,447 (issued on Oct 18, 2022)

US 11,479,747 (issued on Oct 25, 2022)

CA 2,711,854 (issued on Mar 21, 2023)


Additional US and international patents pending

Protocols:
OmniLyse® Ultra-rapid Cell Lysis Protocol


Data & Images:




Publications Referencing OmniLyse® Lysis Kits:

Near-Quantitative Sampling of Genomic DNA from Various Food-Borne Eubacteria

Bead Beating-Based Continuous Flow Cell Lysis in a Microfluidic Device

Aminoglycoside-modifying Enzymes Determine the Innate Susceptibility to Aminoglycoside Antibiotics in Rapidly Growing Mycobacteria

Variability in DNA Polymerase Efficiency: Effects of Random Error, DNA Extraction Method, and Isolate Type

Solution-based Circuits Enable Rapid and Multiplexed Pathogen Detection

Proximal Bacterial Lysis and Detection in Nanoliter Wells Using Electrochemistry

Optimized Templates for Bottom-Up Growth of High-Performance Integrated Biomolecular Detectors

Ipso-Hydroxylation and Subsequent Fragmentation: a Novel Microbial Strategy To Eliminate Sulfonamide Antibiotics

Tuning the Bacterial Detection Sensitivity of Nanostructured Microelectrodes

Point of Care Diagnostics: Status and Future

Mechanical Disruption of Lysis-Resistant Bacterial Cells by Use of a Miniature, Low-Power, Disposable Device Point-of-Care Nucleic Acid Testing For Infectious Diseases

Point-of-Care Nucleic Acid Testing For Infectious Diseases

Continuous-Flow, Rapid Lysis Devices for Biodefense Nucleic Acid Diagnostic Systems

WetLab-2: Quantitative PCR Tools for Spaceflight Studies of Gene Expression aboard the International Space Station

Ch 8: Microfluidic Diagnostics for Low-resource Settings: Improving Global Health without a Power Cord

Development Status of the WetLab-2 Project: New Tools for On-orbit Real-time Quantitative Gene Expression


Low-Cost Microdevices for Point-of-Care Testing


Refining Sample Prep for Molecular DX


Use of a Disposable Lysis Device and Capture of Unamplified mycobacterial rRNA on A Liquid Bead Array for Species Determination from Liquid Cultures


Real-Time Sample Prep on the Horizon


Novel Applications for Sample Preparation: Tool Providers Launch Innovative Products to Meet Researchers' Protein-Related Demands