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Lateral Flow Reagent Dispenser

Product Overview:
ClaremontBio's Automated Lateral Flow Reagent Dispenser (ALFRD) offers an inexpensive and reliable alternative for dispensing reagents onto membranes or paper. This ALFRD unit is ideal for development or small-scale production Lateral Flow or paper-based fluidic applications. ClaremontBio's Lateral Flow Reagent Dispenser works with a syringe pump to drive reagents onto the nitrocellulose.

Highlighted Data from Publications using CBIO's Automated Lateral Flow Reagent Dispenser (ALFRD):

Title: Lectin-based Lateral Flow Assay: Proof-of-Concept

Year: 2016

Journal: Analyst

Authors: Damborsky P, Koczula KM, Gallotta A, Katrlik J

Institution Affiliations : Slovak Academy of Sciences; Xeptagen SpA

eference: Analyst. 2016. 141(23) 6444–6448. doi: 10.1039/C6AN01746K
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Automated Lateral Flow Reagent Dispenser (ALFRD)™




Title: Mitigating the Hook Effect in Lateral Flow Sandwich Immunoassays using Real-time Reaction Kinetics

Year: 2017

Journal: Analytical Chemistry

Authors: Rey EG, O’Dell D, Mehta S, Erickson D

Institution Affiliations : Cornell University

Reference: Analytical Chemistry. 2017. 89(9): 5095-5100. doi: 10.1021/acs.analchem.7b00638

#Automated Lateral Flow Reagent Dispenser (ALFRD)™





Title: Multiplexed Recombinase Polymerase Amplification Assay To Detect Intestinal Protozoa

Year: 2016

Journal: Analytical Chemistry

Authors: Crannell Z, Castellanos-Gonzalez A, Gayatri N, Rojelio M, White AC, Richards- Kortum A

Institution Affiliations : University of Texas Medical Branch; Baylor College of Medicine; Rice University

Reference: Analytical Chemistry. 2016. 88, 1610-1616; doi:10.1021/acs.analchem.5b03267

#Automated Lateral Flow Reagent Dispenser (ALFRD)™








Title: Aptamer-Phage Reporters for Ultrasensitive Lateral Flow Assays

Year: 2015

Journal: Analytical Chemistry

Authors: Adhikari M, Strych U, Kim J, Goux H, Dhamane S, Poongavanam MV, Hagström AEV, Kourentzi K, Conrad JC, Willson RC

Institution Affiliations: University of Houston; Centro de Biotecnología FESMA, Tecnológico de Monterrey

Reference: Analytical Chemistry. 2016. 87, 11660-11665; doi:10.1021/acs.analchem.5b00702

#Automated Lateral Flow Reagent Dispenser (ALFRD)™







Title: IronPhone: Mobile Device-Coupled Point-of-Care Diagnostics for Assessment of Iron Status by Quantification of Serum Ferritin

Year: 2017

Journal: Biosensors and Bioelectronics

Authors: Srinivasan B, O’Dell D, Finkelstein JL, Lee S, Erickson D, Mehta S

Institution Affiliations: Cornell University

Reference: Biosensors and Bioelectronics. 2017. 99(15): 115-121 . https://doi.org/10.1016/j.bios.2017.07.038
#Automated Lateral Flow Reagent Dispenser (ALFRD)








Title: Rapid Detection of Escherichia coli O157 and Shiga Toxins by Lateral Flow Immunoassays

Year: 2016

Journal: Toxins

Authors: Wang J, Katani R, Li L, Hegde N, Roberts EL, Kapur V, DebRoy C

Institution Affiliations : Pennsylvania State University

Reference: Toxins. 2016. Mar 25; 92(8). doi:10.3390/toxins8040092

#Automated Lateral Flow Reagent Dispenser (ALFRD)™






Title: Persistent Luminescence Strontium Aluminate Nanoparticles as Reporters in Lateral Flow Assays

Year: 2014

Journal: Analytical Chemistry

Authors: Paterson AS, Raja B, Garvey G, Kolhatkar A, Hagström AEV, Kourentzi K, Lee TR, Willson RC

Institution Affiliations : University of Houston

Reference: Analytical Chemistry. 2014. 86(19) . doi:10.1021/ac5012624

#Automated Lateral Flow Reagent Dispenser (ALFRD)™






Title: NutriPhone: A Mobile Platform for Low-Cost Point-of-Care Quantification of Vitamin B12 Concentrations

Year: 2016

Journal: Nature Scientific Reports

Authors: Lee S, O’Dell D, Hohenstein J, Colt S, Mehta S, Erickson D

Institution Affiliations : Cornell University

Reference: Nature Scientific Reports. 2016. Jun 15; 6:28237. doi:10.1038/srep28237

#Automated Lateral Flow Reagent Dispenser (ALFRD)™








Title
: Towards a Point-of-Care strip Test to Diagnose Sickle Cell Anemia

Year: 2017

Journal: PLoS One

Authors: Bond M, Hunt B, Flynn B, Huhtinen P, Ware R, Richards- Kortum R

Institution Affiliations : Rice University; PerkinElmer; Cincinnati Children’s Hospital Medical Center

Reference: PLoS One. 2017. May 16. https://doi.org/10.1371/journal.pone.0177732

#Automated Lateral Flow Reagent Dispenser (ALFRD)™






Title: Sensitive Detection of Norovirus Using Phage Nanoparticle Reporters in Lateral-Flow Assay

Year: 2015

Journal: PLoS ONE

Authors: Hagström AEV, Garvey G, Paterson AS, Dhamane S, Adhikari M, Estes MK, Strych U, Kourentzi K, Atmar RL, Willson RC

Institution Affiliations : University of Houston; Baylor College of Medicine; Houston Methodist Research Institute

Reference: PLoS One. 2015. 10(5). 1-11; doi:10.1371/journal.pone.0126571

#Automated Lateral Flow Reagent Dispenser (ALFRD)™






Title: Simple System for Isothermal DNA Amplification Coupled to Lateral Flow Detection

Year: 2013

Journal: PLoS ONE

Authors: Roskos K, Hickerson AI, Lu H-W, Ferguson TM, Shinde DN, Klaue Y, Niemz A

Institution Affiliations : Keck Graduate Institute; Claremont BioSolutions

Reference: PLoS ONE. 2013. 8 (7): e69355.; doi:10.1371/journal.pone.0069355

#Automated Lateral Flow Reagent Dispenser (ALFRD)™









Key Features

• Reproducible, well defined test lines
• No heating of reagents
• Non-contact, adjustable dispense tips
• Dispense colloidal conjugate or viscous solutions
• Interchangeable and low-cost dispense heads and tips
• Adjustable dispense volume
• Simultaneous dispensing of up to 4 lines (customizable for additional lines)
• Accommodates 30 cm membrane length of varying width
• Use your existing syringe pump or purchase from ClaremontBio
• Coming Soon: Adaptable to dispense dots for flow-through assays


Video Protocol:



User Manual:

ClaremontBio's Lateral Flow Reagent Dispenser User Manual

Core Assay Development Starter Kit for Lateral Flow ClaremontBio's Lateral Flow Reagent Dispenser ALFRD and Syringe Pump Core Package
PN: 07.600.01 ClaremontBio's Core Assay Development Starter Kit. Everything you need to get started.

PN: 07.711.01 Automated Lateral Flow Reagent Dispenser (ALFRD) instrument. Includes standard accessories and power source.

PN: 07.701.01 Core ALFRD package includes dispenser, syringe pump (does not include rack), and standard accessories

ALFRD, Syringe Pump and 10 Channel Rack - Package ALFRD Package, Beyond Basic (over $900 savings) ALFRD Package, Complete (over $1,500 savings)

PN: 07.700.10 Basic ALFRD package includes dispenser, syringe pump with rack, and standard accessories

PN: 07.700.20 Beyond Basic ALFRD package includes dispenser, syringe pump with rack, full assortment of heads and premium replacement  accessories. PN: 07.700.30 Complete ALFRD package includes dispenser, syringe pump with rack, full assortment of heads, premium replacement accessories and our Core assay development starter kit.