
Product Overview: ClaremontBio's OmniLyse® family of Lysis Kits are ultra-rapid and mechanical cell disruptors, capable of lysis in roughly one minute with even hard-to-lyse gram-positive organisms and is hailed by the USDA as the best available method.
"OmniLyse methods provided the greatest consistent yield of genomic DNA."- Irwin et al. BMC Microbiology (2014) 14:326 - USDA publication - Near-Quantitative Sampling of Genomic DNA from Various Food-Borne Eubacteria
The OmniLyse® Lysis Kits utilize a bead beating method to quickly shear open cells without the use of harsh chemicals, wash baths, or a centrifuge. The OmniLyse is operated by a battery pack and can be used anywhere. Capable of disrupting most types of cells, the OmniLyse® Lysis Kit is an excellent fit for various downstream applications. The OmniLyse® Kits are highly customizable and allow for easy integration into systems and applications for commercially available products or in earlier phases of product development.
OmniLyse® Key Features: - Rapidly lyses a wide range of cell types in roughly 1 minute - Works with cells including gram-positive & gram-negative, yeast, mammalian, spores, cysts, and many more -
No chemicals or wash steps make OmniLyse® Kits ideal for sensitive
assays that can be affected by the presence or organic compounds.
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Disposability and portability allow OmniLyse® Kits to be stored under
normal laboratory condition. After use, the kits can then be simply
thrown away without any harm to the environment.
- Can be used and purchased with beads or without - Various configurations available to best suit your sample - No centrifugation steps - Simple protocol
Protocols: OmniLyse® Ultra-rapid Cell Lysis Protocol
Data & Images:

Publications Referencing OmniLyse® Lysis Kits:
Near-Quantitative Sampling of Genomic DNA from Various Food-Borne Eubacteria
Bead Beating-Based Continuous Flow Cell Lysis in a Microfluidic Device
Aminoglycoside-modifying
Enzymes Determine the Innate Susceptibility to Aminoglycoside
Antibiotics in Rapidly Growing Mycobacteria
Variability in DNA Polymerase Efficiency: Effects of Random Error, DNA Extraction Method, and Isolate Type
Solution-based Circuits Enable Rapid and Multiplexed Pathogen Detection
Proximal Bacterial Lysis and Detection in Nanoliter Wells Using Electrochemistry
Optimized Templates for Bottom-Up Growth of High-Performance Integrated Biomolecular Detectors
Ipso-Hydroxylation and Subsequent Fragmentation: a Novel Microbial Strategy To Eliminate Sulfonamide Antibiotics
Tuning the Bacterial Detection Sensitivity of Nanostructured Microelectrodes
Point of Care Diagnostics: Status and Future
Mechanical
Disruption of Lysis-Resistant Bacterial Cells by Use of a Miniature,
Low-Power, Disposable Device Point-of-Care Nucleic Acid Testing For
Infectious Diseases
Point-of-Care Nucleic Acid Testing For Infectious Diseases
Continuous-Flow, Rapid Lysis Devices for Biodefense Nucleic Acid Diagnostic Systems
WetLab-2: Quantitative PCR Tools for Spaceflight Studies of Gene Expression aboard the International Space Station
Ch 8: Microfluidic Diagnostics for Low-resource Settings: Improving Global Health without a Power Cord
Development Status of the WetLab-2 Project: New Tools for On-orbit Real-time Quantitative Gene Expression
Low-Cost Microdevices for Point-of-Care Testing
Refining Sample Prep for Molecular DX
Use
of a Disposable Lysis Device and Capture of Unamplified mycobacterial
rRNA on A Liquid Bead Array for Species Determination from Liquid
Cultures
Real-Time Sample Prep on the Horizon
Novel
Applications for Sample Preparation: Tool Providers Launch Innovative
Products to Meet Researchers' Protein-Related Demands
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