SimplePrep® X8 & X1

The Instrument
ClaremontBio’s SimplePrep® X8 or X1 is an all-in-one automated cell lysis and nucleic acid extraction instrument designed to rapidly isolate DNA or RNA from hard-to-lyse bacterial samples within complex sample matrices in only 6 minutes. Samples are rapidly lysed and subsequently purified in a true hands-free workflow without the need for tedious centrifuge steps or time-consuming incubation periods. The SimplePrep® instrument utilizes self-contained, disposable cartridges to rapidly extract nucleic acids from 1 to 8 samples all-at-once, providing high yields of PCR-ready nucleic acids even when high concentrations of PCR inhibitors are present. Controlled by a programmable touch-screen interface, protocols can be stored and recalled quickly for changing sample types without any additional instrumentation.

The Cartridges
SimplePrep® cartridges utilize ClaremontBio’s proprietary miniaturized mechanical lysis technology that provide rapid lysis of all types of bacterial samples, followed by the isolation of nucleic acids via binding, washing, and elution of the same beads used for lysis. Employing these unique, disposable (RoHS compliant) micro-motors, automated extraction of nucleic acids can be attained from extremely challenging sample types, such as sporulated gram-positive bacteria or various other hard-to-lyse bacterial samples (such as Clostridium difficile spores) within complex matrices such as stool or soil.