
Lateral Flow Reagent Dispenser
Product Overview: ClaremontBio's Automated Lateral Flow Reagent Dispenser (ALFRD) offers an inexpensive and reliable alternative for dispensing reagents onto membranes or paper. This ALFRD unit is ideal for development or small-scale production Lateral Flow or paper-based fluidic applications.
ClaremontBio's Lateral Flow Reagent Dispenser works with a syringe pump to drive reagents onto the nitrocellulose.
Highlighted Data from Publications using CBIO's Automated Lateral Flow Reagent Dispenser (ALFRD):
Title: Lectin-based
Lateral Flow Assay: Proof-of-Concept
Year: 2016
Journal: Analyst
Authors:
Damborsky P, Koczula KM, Gallotta A, Katrlik J
Institution
Affiliations
: Slovak
Academy of Sciences;
Xeptagen SpA
eference: Analyst. 2016.
141(23) 6444–6448.
doi:
10.1039/C6AN01746K
#Automated
Lateral Flow Reagent Dispenser (ALFRD)™
Title:
Mitigating the
Hook Effect in Lateral Flow Sandwich Immunoassays using Real-time Reaction
Kinetics
Year: 2017
Journal: Analytical Chemistry
Authors:
Rey EG, O’Dell D, Mehta S, Erickson D
Institution
Affiliations
: Cornell
University
Reference: Analytical Chemistry. 2017.
89(9): 5095-5100.
doi:
10.1021/acs.analchem.7b00638
#Automated
Lateral Flow Reagent Dispenser (ALFRD)™
Title:
Multiplexed
Recombinase Polymerase Amplification Assay To Detect Intestinal Protozoa
Year: 2016
Journal: Analytical Chemistry
Authors:
Crannell Z,
Castellanos-Gonzalez A,
Gayatri N, Rojelio M,
White AC, Richards-
Kortum A
Institution
Affiliations
: University
of Texas Medical Branch; Baylor College of Medicine; Rice University
Reference: Analytical Chemistry. 2016.
88,
1610-1616; doi:10.1021/acs.analchem.5b03267
#Automated
Lateral Flow Reagent Dispenser (ALFRD)™

Title: Aptamer-Phage Reporters for Ultrasensitive Lateral Flow Assays
Year: 2015
Journal: Analytical Chemistry
Authors: Adhikari M, Strych U, Kim J, Goux H, Dhamane S, Poongavanam MV, Hagström AEV, Kourentzi K, Conrad JC, Willson RC
Institution Affiliations: University of Houston; Centro de Biotecnología FESMA, Tecnológico de Monterrey
Reference: Analytical Chemistry. 2016. 87, 11660-11665; doi:10.1021/acs.analchem.5b00702
#Automated Lateral Flow Reagent Dispenser (ALFRD)™

Title:
IronPhone:
Mobile Device-Coupled Point-of-Care Diagnostics for Assessment of Iron Status
by Quantification of Serum Ferritin
Year: 2017
Journal: Biosensors and Bioelectronics
Authors:
Srinivasan B, O’Dell D, Finkelstein JL, Lee S, Erickson D, Mehta S
Institution
Affiliations: Cornell University
Reference: Biosensors and Bioelectronics. 2017.
99(15): 115-121
.
https://doi.org/10.1016/j.bios.2017.07.038 #Automated
Lateral
Flow Reagent Dispenser (ALFRD)
™

Title:
Rapid Detection
of Escherichia coli O157 and Shiga Toxins by Lateral Flow Immunoassays
Year: 2016
Journal: Toxins
Authors:
Wang J,
Katani R,
Li L,
Hegde N,
Roberts EL,
Kapur V, DebRoy C
Institution
Affiliations
: Pennsylvania
State University
Reference: Toxins. 2016.
Mar 25;
92(8).
doi:10.3390/toxins8040092
#Automated
Lateral Flow Reagent Dispenser (ALFRD)™

Title:
Persistent
Luminescence Strontium Aluminate Nanoparticles as Reporters in Lateral Flow
Assays
Year: 2014
Journal:
Analytical Chemistry
Authors:
Paterson AS, Raja B, Garvey G,
Kolhatkar A, Hagström AEV, Kourentzi K, Lee TR, Willson RC
Institution
Affiliations
: University
of Houston
Reference: Analytical Chemistry. 2014.
86(19)
.
doi:10.1021/ac5012624
#Automated
Lateral Flow Reagent Dispenser (ALFRD)™

Title:
NutriPhone: A Mobile
Platform for Low-Cost Point-of-Care Quantification of Vitamin B12
Concentrations
Year: 2016
Journal: Nature Scientific Reports
Authors:
Lee S, O’Dell D,
Hohenstein J,
Colt S, Mehta S, Erickson D
Institution
Affiliations
: Cornell
University
Reference: Nature Scientific Reports. 2016.
Jun 15; 6:28237. doi:10.1038/srep28237
#Automated
Lateral Flow Reagent Dispenser (ALFRD)™

Title:
Towards
a Point-of-Care strip Test to Diagnose Sickle Cell Anemia
Year: 2017
Journal: PLoS One
Authors:
Bond M, Hunt B, Flynn B,
Huhtinen P,
Ware R, Richards-
Kortum R
Institution
Affiliations
: Rice
University; PerkinElmer; Cincinnati Children’s Hospital Medical Center
Reference: PLoS One. 2017.
May 16.
https://doi.org/10.1371/journal.pone.0177732
#Automated
Lateral Flow Reagent Dispenser (ALFRD)™

Title:
Sensitive
Detection of Norovirus Using Phage Nanoparticle Reporters in Lateral-Flow Assay
Year: 2015
Journal: PLoS ONE
Authors:
Hagström AEV,
Garvey G, Paterson AS,
Dhamane S, Adhikari M,
Estes MK,
Strych U, Kourentzi K, Atmar RL, Willson RC
Institution
Affiliations
: University
of Houston; Baylor College of Medicine; Houston Methodist Research Institute
Reference: PLoS One. 2015.
10(5).
1-11; doi:10.1371/journal.pone.0126571
#Automated
Lateral Flow Reagent Dispenser (ALFRD)™

Title: Simple
System for Isothermal DNA Amplification Coupled to Lateral Flow Detection
Year: 2013
Journal: PLoS ONE
Authors:
Roskos K, Hickerson AI,
Lu H-W, Ferguson TM,
Shinde DN, Klaue Y,
Niemz A
Institution
Affiliations
: Keck
Graduate Institute; Claremont
BioSolutions
Reference:
PLoS
ONE. 2013.
8
(7):
e69355.; doi:10.1371/journal.pone.0069355
#Automated
Lateral Flow Reagent Dispenser (ALFRD)™

Key Features
• Reproducible, well defined test lines • No heating of reagents • Non-contact, adjustable dispense tips • Dispense colloidal conjugate or viscous solutions • Interchangeable and low-cost dispense heads and tips • Adjustable dispense volume • Simultaneous dispensing of up to 4 lines (customizable for additional lines) • Accommodates 30 cm membrane length of varying width • Use your existing syringe pump or purchase from ClaremontBio • Coming Soon: Adaptable to dispense dots for flow-through assays
Video Protocol:
User Manual:
ClaremontBio's Lateral Flow Reagent Dispenser User Manual
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